Plant pharmacological studies have suggested that Calendula extracts have anti-viral, anti-genotoxic and anti-inflammatory properties. Calendula in suspension or in tincture is used topically to treat acne, reducing inflammation, controlling bleeding and soothing irritated tissue. There is "limited evidence" that calendula cream or ointment is effective in treating radiation dermatitis. In a randomized study of 254 radiation patients, topical application of 4% calendula ointment resulted in far fewer occurences of Grade 2 or higher dermatitis than occurred in the group using trolamine. Calendula users also experienced less radiation-induced pain and fewer breaks in treatment.
Calendula has been used traditionally for abdominal cramps and constipation. In experiments with rabbit jejunum the aqueous-ethanol extract of Calendula officinalis flowers was shown to have both spasmolytic and spasmogenic effects, thus providing a scientific rationale for this traditional use. An aqueous extract of Calendula officinalis obtained by a novel extraction method has demonstrated anti-tumor (cytotoxic) activity and immunomodulatory properties (lymphocyte activation) in vitro, as well as anti-tumor activity in mice.
Source : http://en.wikipedia.org/wiki/Calendula
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